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HEPATOLOGY<\/strong><\/p>\n <\/p>\n Transplantation<\/em><\/p>\n Survival After Liver Transplantation: An International Comparison Between the United States and the United Kingdom in the Years 2008-2016 <\/p>\n American Journal of Transplantation <\/p>\n Pediatric Blood and Cancer <\/p>\n SURGERY<\/strong><\/p>\n <\/p>\n Transplantation <\/p>\n Annals of Surgery <\/p>\n Liver Transplantation<\/em><\/p>\n Non-invasive Risk Stratification for NAFLD Among Living Liver Donor Candidates: A Proposed Algorithm <\/strong><\/p>\n To reduce waitlist mortality, living donor liver transplantation (LDLT) has increased over the past decade in US, however, not at a rate sufficient to completely mitigate organ shortage. As a result, there are ongoing efforts to expand the living liver donor pool. Read more<\/a>.<\/p>\n <\/p>\n ANESTHESIOLOGY AND CRITICAL CARE<\/strong><\/p>\n <\/p>\n HPB<\/em><\/p>\n A decline in functional status while awaiting liver transplantation is predictive of increased post-transplantation mortality<\/strong><\/p>\n Background:\u00a0Functional status (FS) is dynamic and changes over time. We examined how changes in FS while awaiting liver transplantation influence post-transplant outcomes. Read more<\/a>.<\/p>\n <\/p>\n Journal of Surgical Research <\/em><\/p>\n Perioperative Skeletal Muscle Fluctuations in High-Acuity Liver Transplantation<\/strong><\/p>\n Background: Frailty has been implicated as a negative predictor of Liver Transplant (LT) outcomes. However, an understanding of changes in patient muscle mass peri-LT, and their effect in high-acuity patients remains lacking.\u00a0We examined the impact of perioperative muscle mass changes (\u0394SMI) on high-acuity (MELD \u226535) LT recipients. Read more<\/a>.<\/p>\n <\/p>\n World Journal of Surgery<\/em><\/p>\n Safety and Efficacy of Tranexamic Acid to Minimise Perioperative Bleeding in Hepatic Surgery: A Systematic Review and Meta-Analysis<\/strong><\/p>\n Introduction: Perioperative bleeding poses a major risk during liver surgery, which can result in increased transfusion requirements, morbidity, and mortality. Tranexamic acid (TXA) effectively reduces perioperative bleeding and transfusion requirements in trauma patients. However, there remains a lack of evidence of its use in liver surgery. This meta-analysis of randomised controlled trials evaluated the efficacy and safety of TXA in liver resection and transplantation. Read more<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":" This month\u2019s key articles were selected by Ryan Chadha, David Victor, and Young In Yoon. HEPATOLOGY Transplantation Survival After Liver Transplantation: An International Comparison Between the United States and the United Kingdom in..<\/p>\n","protected":false},"featured_media":17978,"template":"","acf":[],"_links":{"self":[{"href":"https:\/\/old.ilts.org\/api\/wp\/v2\/news\/18884"}],"collection":[{"href":"https:\/\/old.ilts.org\/api\/wp\/v2\/news"}],"about":[{"href":"https:\/\/old.ilts.org\/api\/wp\/v2\/types\/news"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/old.ilts.org\/api\/wp\/v2\/media\/17978"}],"wp:attachment":[{"href":"https:\/\/old.ilts.org\/api\/wp\/v2\/media?parent=18884"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n<\/strong>Background:\u00a0Compared with the United States, risk-adjusted mortality in the United Kingdom has historically been worse in the first 90 d following liver transplantation (LT) and better thereafter. In the last decade, there has been considerable change in the practice of LT internationally, but no contemporary large-scale international comparison of post-transplant outcomes has been conducted. This study aimed to determine disease-specific short- and long-term mortality of LT recipients in the United States and the United Kingdom. Read more.<\/a><\/p>\n
\n<\/em>HOPE in Action: A Prospective Multicenter Pilot Study of Liver Transplantation from Donors with HIV to Recipients with HIV
\n<\/strong>Liver transplantation (LT) from donors-with-HIV to recipients-with-HIV (HIV D+\/R+) is permitted under the HOPE Act. There are only 3 international single case reports of HIV D+\/R+ LT, each with limited follow-up. We performed a prospective multicenter pilot study comparing HIV D+\/R+ to donors-without-HIV to recipients-with-HIV (HIV D-\/R+) LT. We quantified patient survival, graft survival, rejection, serious adverse events (SAEs), HIV breakthrough, infections, and malignancies, using Cox and negative binomial regression with inverse probability of treatment weighting. Read more.<\/a>
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\n<\/em>Waitlist mortality and post-liver transplant outcomes of pediatric patients with hepatocellular carcinoma and hepatoblastoma in the United States
\n<\/strong>Background:\u00a0Liver transplantation (LT) is offered in cases of advanced disease for both pediatric patients with hepatoblastoma (HBL) and those with hepatocellular carcinoma (HCC). Current United States organ allocation priorities differ between the two groups.Methods:\u00a0We retrospectively examined the waitlist and posttransplant outcomes of pediatric LT candidates with HBL and HCC using the United Network for Organ Sharing registry (February 2002 to September 2020). Read more<\/a>.<\/p>\n
\n<\/em>The Need to Update Endpoints and Outcome Analysis in the Rapidly Changing Field of Liver Transplantation
\n<\/strong>Liver transplantation (LT) survival rates have continued to improve over the last decades, mostly due to the reduction of mortality early after transplantation. The advancement is facilitating a liberalization of access to LT, with more patients with higher risk profiles being added to the waiting list. Read more<\/a>.<\/p>\n
\n<\/em>Post-Transplant Hepatocellular Carcinoma Surveillance: A Cost-Effectiveness AndCost-Utility Analysis
\n<\/strong>Objective:\u00a0Assess cost-effectiveness and -utility associated with post-transplant HCC\u00a0surveillance\u00a0compared to standard follow-up.Summary Background Data:\u00a0Despite the lack of prospective clinical data, expert consensus recommends post-transplant\u00a0surveillance\u00a0to detect hepatocellular carcinoma (HCC) recurrence in a latent phase, while it might be amenable to curative-intent therapy. Read more<\/a>.<\/p>\n